Synthetic research compound for laboratory use. Intended exclusively for qualified research environments.
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Research use only. Not for human or veterinary use.
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Store at −20°C, protected from light and moisture. Allow the vial to reach ambient temperature before opening. Handle according to your laboratory’s standard operating procedures for research chemicals.
Third-party references
Three original studies on MOTS-c discovery, cellular stress signaling, and muscle biology. These sources do not establish safety or effectiveness for human or veterinary use, and do not verify an Arete batch.
Cell Metabolism
Cell and animal research MOTS-c
The original study identified a 16-amino-acid mitochondrial-derived compound and examined folate-cycle, purine-pathway, and AMPK signaling in cells and mice. The findings concern the study materials, not Arete products.
2015 Lee C et al.
DOI: 10.1016/j.cmet.2015.02.009
PMID: 25738459
Cell Metabolism
Cellular mechanism research MOTS-c
Cell experiments examined MOTS-c movement into the nucleus during metabolic stress and its association with stress-responsive gene regulation, including AMPK-dependent signaling. This is mechanistic research, not product testing.
2018 Kim KH et al.
DOI: 10.1016/j.cmet.2018.06.008
PMID: 29983246
Nature Communications
Preclinical and observational research MOTS-c
Researchers studied muscle metabolism and physical capacity in mice, cellular stress responses, and naturally occurring MOTS-c during human exercise. The human observations were not a trial of administered MOTS-c.
2021 Reynolds JC et al.
DOI: 10.1038/s41467-020-20790-0
Nature Communications 12, 470
Headings summarize the research topics; linked records provide the original publication details. References do not imply endorsement of Arete or replace a lot-specific certificate of analysis.
